|
Curves dose-answer
Once it was proved the efficacy of
the mother tincture's formulation by the with animal's
experimentation, it has been made a large specter
with different dilutions and vehicles.
From this specter it obtained the results of Table
1: "Curve Dose - Answer"
|
Dilución
|
PF1
(90% Solvente 1. 10% TM)
|
PF2
(85% Solvente 1, 5% Solvente 2, 10% TM)
|
PF3
(80% Solvente 1, 10% Solvente 2, 10% TM)
|
|
I.E.
|
% Inhib
|
I.E.
|
% Inhib
|
I.E.
|
% Inhib
|
|
1/10
|
0.22
|
77.0
|
0.24
|
76.25
|
0.23
|
77
|
|
1/25
|
0.35
|
64.8
|
0.44
|
55.8
|
0.46
|
53.6
|
|
1/50
|
0.60
|
39.9
|
0.67
|
33
|
0.62
|
38.2
|
|
1/100
|
0.87
|
12.8
|
0.78
|
21.9
|
0.66
|
34.2
|
|
1/200
|
0.98
|
2.2
|
0.96
|
0
|
0.73
|
27
|
|
1/400
|
1.03
|
0
|
0.99
|
0
|
0.86
|
13.8
|
TABLE 1: "Curve Dose - Answer"
As it is shown in Figure 1: "Graphic Curve
Dose - Answer" the optimum dose (best therapeutic
effect with no side effects) is 1/400 and the optimum
formulation is PF3, the one showed a percentage
of cellular proliferation of inhibition of 13.8
%, at this dose.
Figure 1: "Graphic
Curve Dose - Answer"
Making an extrapolation of the obtained results the
1/400 dilution is the same to a dosage of 240 drops
per day. This result is obtained considering the volume
of a drop is 0.05 ml., so 240 drops are 12 ml. of
Green Sap solved in blood (adult's blood volume =
5.000 ml).
The dosage administered of 12 ml. of Basqüadé
is solved in 5.000 ml. of blood, that is the equivalent
of 1 ml. in 416 ml of blood.
It's important to remark that
in this study was proved that the product must be
shaken before its administration for a good homogenization
of it, according to its organoleptic properties.
|
